KTH / Chemistry / Organic
Chemistry / Education / DCC
Dynamic Combinatorial Chemistry (FKD3040) 2p
Dynamic Combinatorial Chemistry is given as a graduate course
(PhD-course) by the Division of Organic Chemistry, School of Chemical
Sciences, KTH. The course is open to PhD-students at KTH, other universities,
research institutes, and industry. Advanced undergraduate students
can be admitted if places are available. 2 points/credits (3hp) will be awarded upon completion of the course. Teaching
will be given in English.
Course Objectives
The course is objected to provide students with an advanced
level of understanding regarding the principles of dynamic combinatorial chemistry (DCC), and applications of DCC systems in bio-,
nano- and materials science. Students will be guided/inspired
to understand the properties and importance of dynamic reactions, and their translation to function in combinatorial systems.
Prerequisites
Students admitted to the course are expected to have advanced
comprehension in organic chemistry, physical chemistry, inorganic
chemistry, biochemistry, and analytical chemistry.
Application
Application for the course should be made before June 28,
2007, to Olof Ramström (ramstrom@kth.se).
Schedule 2007
The course is arranged as a condensed lecture series comprising six individual
lectures (1 x 60 min). All lectures will be given by internationally renowned experts in the field.
All lectures will take place in Lecture Hall F3,
Lindstedtsvägen 26, on June 29, 2007.
| 1 |
Dr. Fredrik Rahm
AstraZeneca R&D
Södertälje, Sweden
|
Combinatorial Chemistry in the Drug Discovery Process
Lecture 1 (pdf)
|
| 2 |
Prof. Jerermy K. M. Sanders
University of Cambridge
UK |
Dynamic Combinatorial Chemistry – a General Introduction
Lecture 2 (pdf) |
| 3 |
Prof. Ulrich Lüning
Christian Albrechts Universität
Kiel, Germany |
Dynamic Combinatorial Macrocyclic Chemistry for Receptor Discovery
Lecture 3 (pdf) |
| 4 |
Dr. Ivan Huc
European Institute of Chemistry and Biology
Bordeaux, France |
Dynamic Reactions and Folding Processes
Lecture 4 (pdf) |
| 5 |
Prof. Sabine Flitsch
University of Manchester
UK |
Dynamic Combinatorial Discovery of Bioactive Compounds
Lecture 5 (pdf) |
| 6 |
Dr. Sijbren Otto
University of Cambridge
UK |
Approaches to Dynamic Library Analysis
Lecture 6 (pdf) |
All presentations are password-protected. Please contact Olof Ramström for password. Usage of lecture material is subject to permission from each lecturer.
Examination
Required participation in all lectures.
Take-home assignment consisting in the following:
- Prepare a microreview (max. 5 pages) on any aspect of DCC, and revise it according to a referee report.
- Act as a referee on a microreview from another participant.
Microreview due before
September 12, 2007
EXAMINATION MAP
The referee report should address the following:
- Scientific correctness: Check contents for misconceptions and errors.
- References: Appropriate reference to scientific literature.
- Presentation: Language, figures, text format, length etc.
- Recommendation: "Publish" with minor/major revision, etc.
Send the referee report direct to Olof Ramström when finished.
November 2007: All participants have passed the examination.
Participating course leader
Olof Ramström
KTH
Chemistry
Organic Chemistry
Teknikringen 30
S-100 44 Stockholm
Phone: 08-7906915
Fax: 08-7912333
Email: ramstrom@kth.se |
Welcome!
Olof
|
